| Pathway Id | ko00270 |
| Class & Sub-Class | Class: Metabolism Sub-Class: Amino acid metabolism |
| Description | Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants; cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals; methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid; which animals cannot synthesize. In bacteria and plants; methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM); synthesized from methionine and ATP; is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034]. Source: KEGG Database |
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